Full STI screen (comprehensive sexually transmitted infection screen)
A set of tests for the common sexually transmitted infections — usually HIV, syphilis, chlamydia and gonorrhoea — for people who want a thorough check.
✓ Medically reviewed by a GMC-registered consultant · last reviewed September 2026 · next review September 2027 · how we review
In short
- A full screen usually covers HIV, syphilis, chlamydia and gonorrhoea — but not every infection, so ask what is included.
- Timing is critical: a test done inside the window period can miss an early infection, so retesting is sometimes needed.
- It is designed for people without symptoms; symptoms usually need a consultation and examination instead.
- Free, confidential STI screening exists on the NHS — you do not have to pay to look after your sexual health.
A plain-English summary. The detail — including risks and recovery — is below.
At a glance
A general guide. Your specialist will give you advice for your situation.
Checks for several common infections at once, often without any examination.
A screen is the wrong choice if you have symptoms — you need a consultation and examination instead.
Samples are taken in minutes. A rapid HIV test may give a result straight away; other samples go to the laboratory.
A clear, named route to get results and ask questions.
Samples are taken in minutes. A rapid HIV test may give a result straight away; other samples go to the laboratory.
Laboratory results arrive by your chosen method. You are told whether everything is clear or whether anything...
The service contacts you to arrange treatment, a possible test-of-cure, and confidential help to tell partners.
If you tested very soon after a risk, you may be advised to repeat HIV and syphilis tests after several weeks.

What is a full STI screen?
A full STI screen is a set of tests for the common sexually transmitted infections. In the UK a thorough screen usually covers HIV, syphilis, chlamydia and gonorrhoea. Chlamydia and gonorrhoea are tested from a urine sample or self-taken swabs; HIV and syphilis are tested from blood.
'Full' does not mean every infection. A standard screen does not routinely test for herpes or genital warts (these are usually diagnosed from symptoms), and trichomonas, hepatitis B, hepatitis C or mycoplasma may only be added for certain people or risks. Always ask exactly what is included.
A screen is most useful when you have no symptoms and want reassurance or a routine check. If you do have symptoms, you usually need a consultation and examination rather than a screen alone.
A screen is only as reliable as its timing. Each infection has a 'window period' — the gap between catching it and it showing on a test. A test done too soon can be falsely negative, so you may need to test again later.
Free, confidential STI screening is available to everyone on the NHS. You should never feel you have to pay to check your sexual health, though some people choose a private screen for speed or convenience.
Types, options & approaches
There may be different ways to do this. The right approach depends on the clinical question and your circumstances.
What a 'full' screen usually does and does not include
| Infection | Usually included? |
|---|---|
| HIV | Yes (blood) |
| Syphilis | Yes (blood) |
| Chlamydia and gonorrhoea | Yes (urine or swab) |
| Herpes / genital warts | No — diagnosed from symptoms |
| Hepatitis B/C, trichomonas, mycoplasma | Only if added for your risk |
Always confirm the exact list before you assume you have been 'fully' checked.
Preparing for your test
- Check what infections the screen includes and whether throat or rectal samples are offered.
- Avoid passing urine for about 1–2 hours beforehand if a urine sample is needed.
- Know roughly when you last had sex, as timing decides whether the screen is reliable yet.
- Tell the service about any symptoms — you may need a consultation rather than just a screen.
- Decide how you want your results and whether you want to use a chosen name.
- If using a postal kit, read the instructions carefully so samples are taken correctly.
- If you might have been exposed to HIV in the last 72 hours, seek urgent advice about prevention (PEP) rather than waiting to test.
What happens
For chlamydia and gonorrhoea you give a urine sample or take a swab yourself (for example a vaginal swab, or a throat or rectal swab if relevant). For HIV and syphilis a small blood sample is taken, usually from the arm, or as a finger-prick in some home kits.
At a clinic, samples are taken in private and you can ask questions. With a postal kit, you take the samples at home and post them to the laboratory in the packaging provided.
Some tests, such as a rapid HIV test, can give a result within minutes. Most laboratory results come back within a few days to about two weeks, by text, phone, app or your chosen method. If anything is positive, the service will contact you to arrange treatment and advice.
Is this test right for me?
A good consultation should explore whether it's the right choice for you now — including reasons to wait or consider something else.
May not be suitable if…
- A screen is the wrong choice if you have symptoms — you need a consultation and examination instead.
- It cannot reassure you if taken inside the window period after a recent risk.
- It does not diagnose herpes or warts, which are usually identified from symptoms.
- It is not a substitute for urgent care if you are acutely unwell or had a recent high-risk HIV exposure.
Delay or rearrange if…
- Mainly for timing: testing very soon after a risk may need repeating after the window period.
- If you have just finished antibiotics, some results may be affected — ask the service.
- If you have symptoms, do not delay — seek a consultation promptly.
- If acutely unwell or recently exposed to HIV, seek urgent care rather than waiting to screen.
Alternatives to discuss
- A free NHS sexual health clinic if you were considering paying.
- A full consultation and examination if you have symptoms.
- Targeted testing for a single infection if that is all you need.
- Your GP, who can arrange some tests and refer you on.
Before you decide
Use this as a shared-decision checklist. The aim is not just “can this be done?”, but whether it is right for you, now, with the risks and alternatives clearly understood.
What matters most to me?
Think about symptoms, daily life, work, caring responsibilities, sport, fertility, travel, appearance and anxiety — the right choice depends on your priorities, not just the medical facts.
What are all my options?
Ask about waiting, monitoring, medicines, rehabilitation, a smaller or larger procedure, a different test, NHS referral, or a second opinion where that would help.
What would make me pause?
Active infection, pregnancy, unstable medical problems, smoking, medicines that increase bleeding, poor support at home, or feeling pressured are all reasons to slow down and get tailored advice.
What happens if I do nothing today?
For some problems, waiting is safe; for others, delay can make treatment harder. A good consultation should explain the trade-off in plain English.
Benefits
- Checks for several common infections at once, often without any examination.
- Can detect infections that cause no symptoms but can still be passed on or cause harm.
- Reassurance when results are clear, with advice on when to retest.
- Quick and convenient, especially with self-taken or postal samples.
- Opens the door to treatment, vaccination and prevention if anything is found.
Risks & complications
- A test done too early in the window period can be falsely negative.
- A screen does not cover every infection, which can give false reassurance.
- Mild discomfort from a blood test or swab.
- Anxiety while waiting for results.
- An unexpected positive result needing treatment and partner notification.
- Being asked to repeat a sample that was inadequate or unclear.
- Bruising from a blood test.
- A false-positive screening result that needs a confirmatory test, which can be stressful.
- Feeling faint during a blood test.
The biggest pitfall is timing and scope. A normal result only covers the infections tested and only if enough time has passed since exposure. Ask which infections are included, whether throat or rectal samples are needed for you, and when you should retest after a recent risk.
Published figures to discuss
A screen carries no meaningful procedural risk; the key uncertainties are test accuracy and timing. Modern chlamydia and gonorrhoea (NAAT) tests are highly sensitive once past the window period, and HIV and syphilis blood tests are very accurate after enough time. But a test taken too early can be falsely negative, and very rarely a screening test is falsely positive and needs a confirmatory test. Exact figures depend on the specific test and infection, so timing advice matters more than any single number.
| Figure | Reported range | How to interpret it | Source / confidence |
|---|---|---|---|
| False negative because testing was too early | Falls as window periods pass | Chlamydia and gonorrhoea become reliable sooner than HIV, syphilis and hepatitis blood tests; repeat testing may be needed. | Guide sourcesClinical context |
| Infection missed because the wrong sites were sampled | Recognised limitation | A full screen should match your sexual history, including throat and rectal swabs where relevant. | NHS — Visiting a sexual health clinicnhs.ukSource-linked context |
| Positive screen needing confirmation | Expected for some infections | HIV, syphilis and hepatitis screening positives are usually confirmed with further laboratory tests before diagnosis and treatment planning. | NHS — Visiting a sexual health clinicnhs.ukSource-linked context |
| False reassurance after a negative screen | Common misunderstanding | A negative screen only covers the infections tested, the sites sampled and the time since the relevant exposure. | NHS — Visiting a sexual health clinicnhs.ukSource-linked context |
These are literature figures, not a personalised prediction. Your own risks and likely benefits depend on your circumstances, your health, and how your care is carried out and followed up.
What happens afterwards
There is no physical recovery from a screen. 'Afterwards' is about getting your results, retesting if you tested early, and arranging treatment if needed.
- A small bruise from a blood test, or mild soreness from a swab.
- Waiting a week or two for results.
- Being asked to retest if you tested inside the window period.
- No physical after-effects.
Aftercare
- Get your results in the way you agreed and chase them up if you do not hear back.
- If positive, start treatment promptly and complete the full course.
- Avoid sex, or use condoms, for the advised time after treatment.
- Tell recent partners if asked — the clinic can do this anonymously for you.
- Note when to retest if you tested early after a possible exposure.
- Consider hepatitis B vaccination or HIV prevention (PrEP) if relevant.
- Contact a clinic if you develop symptoms while waiting for results.
- Confirm which infections the screen covers
- Avoid urinating for 1–2 hours before a urine sample
- Note your last sexual contact date
- Decide how to receive results
- Read postal-kit instructions carefully if using one
- Plan a retest date if testing early after a risk
- Save the clinic's contact details
⚠ Get urgent help if…
- Unusual discharge, genital sores, lumps, or a rash while waiting for results.
- Pain or burning when passing urine, or pelvic or testicular pain.
- Fever or feeling generally unwell after a possible infection.
- Heavy or unusual bleeding, or new pain during sex.
- A possible HIV exposure in the last 72 hours — seek urgent advice about prevention (PEP).
- A severe reaction to any treatment, such as swelling or breathing difficulty — call 999.
Who to contact: your clinician, clinic or test provider first (keep their number to hand). For urgent advice when you can't reach them, call NHS 111. In an emergency, call 999.
General guidance — it doesn't replace the specific advice your specialist gives you.
Results & realistic expectations
A clear (negative) screen means none of the infections tested for were detected, at the time of testing. It does not rule out an infection caught very recently, and it does not cover infections that were not part of the screen — so check exactly what was included.
If an infection is found, most common STIs are very treatable, often with a short course of medicine. The service will explain treatment, when you can have sex again, whether a test-of-cure is needed, and how partners can be told confidentially.
A screen only reflects your sexual health up to the date of testing and the window periods involved. New partners or new risks mean you may need to test again. People who change partners are often advised to screen every few months; people in a stable, mutually exclusive relationship need testing far less often.
Related tests, treatments or support
A full screen is often combined with a consultation, hepatitis B vaccination, cervical screening reminders, and contraception or HIV-prevention advice. Throat and rectal swabs may be added depending on the kinds of sex you have.
Follow-up & long-term care
If everything is clear you may simply be told so. If you tested early, you may be asked to retest after a window period. If anything is positive, you will be offered treatment, a possible test-of-cure, and confidential partner notification, or referred for specialist care.
- Repeat screening at intervals if you have new or multiple partners.
- Complete any hepatitis B vaccination course started.
- Ongoing HIV-prevention medicine (PrEP) with its monitoring if you take it.
Repeat, follow-on and what comes next
- Tests taken inside the window period routinely need repeating — this is expected, not a failure.
- Inadequate or unclear samples sometimes need retaking.
- A positive screening result may need a confirmatory test before treatment.
- New partners or symptoms mean repeat screening over time is normal.
Ask what happens if the result is unclear or needs repeating, and what is included if further tests or follow-up are needed.
What good aftercare looks like
- A clear, named route to get results and ask questions.
- Honest window-period advice and a retest plan where needed.
- Prompt treatment and a test-of-cure where appropriate.
- Confidential, supportive partner notification.
- Signposting to free NHS services, vaccination and HIV prevention.
What affects the cost
Costs vary a great deal between people and providers, and we don't publish prices. What matters is understanding what drives the cost and making sure your quote is complete. The main things that affect it:
- Whether you use a free NHS service or pay for a private screen.
- Which infections are included, and any extra tests such as hepatitis or extra-genital swabs.
- Whether results are rapid same-day or standard laboratory tests.
- Whether a consultation or examination is included.
- Treatment, confirmatory tests or a test-of-cure if anything is positive.
- Postage and laboratory fees for home kits.
- The exact list of infections tested for.
- Laboratory and sample-handling fees.
- Whether a consultation, examination or advice is included.
- What a positive result triggers, and at what cost (treatment, confirmatory test).
- Cost of repeat or window-period retesting.
- Cost of any vaccination or prevention medicine.
- A reminder that the same screening is free on the NHS.
On the NHS? Full STI screening is free and confidential on the NHS for everyone; a private screen may be chosen for speed or convenience, but you never have to pay to look after your sexual health.
You're entitled to your total cost in writing — including reports, follow-up and what happens if the result is inconclusive — before you decide.
Consent traps and marketing red flags
These are not small details. They are often where patients lose choice, time to reflect, or realistic expectations.
Consent traps
- Not being told which infections are, and are not, included.
- No clear warning that a too-early test can miss infection.
- Being sold a private 'full' panel without mention of free NHS screening.
- No advice on whether throat or rectal samples are needed for you.
- Unclear results process or confidentiality arrangements.
Marketing red flags
- Implying you must pay when free NHS screening exists.
- Claiming a single same-day screen 'rules out everything', ignoring window periods.
- Calling a basic four-infection test 'comprehensive' without naming the gaps.
- Selling expensive panels for infections you are very unlikely to have.
- Offering 'herpes screening' for people without symptoms, which is not recommended.
Choosing a specialist safely
- Check the specialist is on the GMC Specialist Register for this area.
- Make sure they work at a CQC-registered service, and look for membership of the relevant Royal College or professional body.
- You're entitled to time to consider and to have your questions answered before you agree — the specialist who looks after you should explain it, not a salesperson.
- Be wary of pressure: time-limited offers or deposits taken before you've had time to think are red flags, not bargains.
- You're entitled to your total cost in writing — including any follow-up — before you decide.
Questions to ask your medical professional
Take this to your consultation. A good specialist will welcome every one of these.
- Exactly which infections does this screen include, and which does it not?
- Given when I last had sex, is it too early to test — and when should I retest?
- Do I need throat or rectal swabs as well as urine or genital samples?
- How and when will I get my results, and what happens if one is positive?
- If something is positive, can you tell my partners without naming me?
- Should I also consider hepatitis B vaccination or HIV prevention?
- Are you on the GMC Specialist Register for this area, and which Royal College or professional body are you a member of?
- Will you be the specialist who carries out my test, and who looks after me afterwards?
- What are the risks for someone like me, and how often do your own patients have a problem or need it repeated or redone?
- What does a realistic result look like — and what can this test not achieve?
- What are my options, including waiting, doing nothing for now, or choosing a different approach?
- Can I have written information, results and aftercare instructions in a format I can use, including any accessibility or communication support I need?
- What is the total cost in writing, including any follow-ups, and how much time do I have to decide?
Frequently asked questions
Does a 'full' screen test for everything?
How soon after sex can I have a reliable screen?
Is it free?
Can I do it at home?
What if I have symptoms?
Do I need throat or rectal swabs?
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How we made this page
Medically reviewed by a GMC-registered consultant. Written in plain English, checked against NHS, NICE, GMC and relevant Royal College / specialist-society guidance, and kept under review. No clinic paid to appear on this page, and we publish no pricing. This is general information to help you prepare — it is not a substitute for advice from your own clinician. How we review our guides →
Source hierarchy: UK regulator and NHS/NICE guidance first, then relevant Royal College or specialist-society guidance, then peer-reviewed evidence for procedure-specific figures where available.
Sources & standards: NHS — Visiting a sexual health clinic BASHH — Summary guidance on STI testing (2023) Terrence Higgins Trust — Testing for HIV NHS — Find STI testing and treatment NHS — Sexually transmitted infections (STIs)
Reviews reflect patients' experience of care, not clinical outcomes. For procedure volumes and outcome data see PHIN.
Last medically reviewed 2026-09-21. Spotted something wrong or out of date? Report an error in this guide.
Related guides: Express / rapid STI testing · Sexual health (GUM) consultation · Sexually transmitted infection assessment · Bacterial vaginosis (BV) assessment · Hepatitis B and C testing